Not even the most sophisticated instrumental examinations are able to reveal neurofibril aggregates or amyloid senile plaques in a living person. Doctors therefore formulate a diagnosis of Alzheimer's disease only based on the clinic and only after excluding other possible causes of senile dementia.
Given the benefits of early detection, an investigation into the possible presence of dementia should be initiated when a person has increasingly serious difficulties in performing one or more of the following activities:
An early diagnosis of dementia allows a timely intervention on the causes of reversible dementias, as well as the beginning of therapies that can delay the progression of the disease, exploiting the incomplete compromise of its cerebral circuits.(source: Pharmacy thirty-three).